Efficacy of Curcumin Mouth Wash on Gingival Inflammation in Patients with Chronic Gingivitis

Volume 9 , Issue 1 , June 2022 , Pages 1-12

Authors

Chenar A. Mohammad 1

1 Periodontics Department, College of Dentistry, Hawler Medical University, Erbil, Iraq.

DOI logo 10.17656/sdj.10143

Keywords

Abstract

Objective: For gingival disease, various modalities of treatment are available. Turmeric is a novel product obtained from plants that plays a vital role in treating gingival and periodontal diseases. This study aims to evaluate the anti-plaque and anti-inflammatory property effects of curcumin mouthwash (0.1%) on participants with plaque-induced gingivitis.  

Methods: From eighty subjects, sixty participants with generalized gingivitis received meticulous scaling and polishing (S&P) and were divided randomly into 3 groups: Curcumin (CU), Chlorhexidine (CHX), and control (S&P) groups. Clinical parameters: PI, GI, BOP, and salivary IL-1β were assessed at baseline and after 4 weeks of therapy. The rest of the twenty patients with clinically healthy gingiva.      

Results:  The results showed a significant reduction in the mean values of PI, GI, BOP, and Il-1β levels after 4 weeks of therapy as compared to baseline in all 3 groups (p≤0.05), with the highest mean reduction of GI, BOP, and IL-1 β scores detected in the CU when compared to the CHX and S&P groups, and the highest mean reduction of PI scores detected in the CHX group in comparison to the CU and S&P groups (p≤0.05), with significant differences, existed between the 3 groups (p≤0.05).  

Conclusions: CU was more effective than CHX when anti-inflammatory property effects were considered, while CHX was more effective than CU when anti-plaque property effects were considered. Therefore, CU mouthwash can be considered an effective alternative antigingivitis agent to CHX due to its anti-plaque and anti-inflammatory property effects.

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  • Published at1 June 2022

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