Effects of 1,25-hydroxycholecalciferol on Initial and Secondary Stability of the Dental Implant An In Vivo Study

Volume 11 , Issue 2 , August 2024 , Pages 10-17

Authors

Hazha K. Ahmad 1 ; Kawan S. Othman 1

1 Prosthodontics Department, College of Dentistry, University of Sulaimani, Sulaimani, Iraq.

DOI logo 10.17656/sdj.10188

Keywords

Abstract

Objective: This study aims to evaluate the efficacy of vitamin D levels on the stability of dental implants using the AnyCheck® device.
Methods: Fifty-six units of implants were placed for 21 participants (10 male, 11 female). A new damping capacity method device (Anycheck) was used to test the stability of the implants in two periods, first at the time of implant insertion (initial stability) and second after 3-4 months from implant insertion (secondary stability). The implant stability index was set based on the implant stability quotient value (from 0 to 100. After that, all the participants were sent for a Vit D level test. As a result of this test, the participants were divided into two groups: those with Vit D >30 (Normal) and those with Vit D <30 (Deficient). A statistical analysis was performed by using (paired t-test and independent t-test) at a significant level of (p < 0.05).
Results: The initial stability tests showed a non-significant increase in the ISQ mean value for the normal vitamin D group compared to the deficient vitamin D group (73.133, 72.288). The secondary stability tests showed a significant decrease in the ISQ mean value for the normal vitamin D group compared to the vitamin D deficient group (69.3, 72.28).
Conclusions: Within the limitations of this study, the vitamin D level does not significantly improve dental implants' initial and secondary stability. The efficacy of vitamin D on implant osseointegration remains controversial and requires further investigation.

References

  1. Chrcanovic BR, Kisch J, Albrektsson T, Wennerberg A. A retrospective study on clinical and radiological outcomes of oral implants in patients followed up for a minimum of 20 years. Clin Implant Dent Relat Res. 2018;20(2):199-207.
  2. Bosshardt DD, Chappuis V, Buser D. Osseointegration of titanium, titanium alloy and zirconia dental implants: current knowledge and open questions. Periodontol 2000. 2017;73(1):22-40.
  3. Ali TT, Othman KS. Retention evaluation of implant-supported mandibular overdenture using two different attachment systems: an in vitro study. Sulaimani Dent J. 2023;10(3):13-23.
  4. Branemark PI. Osseointegration and its experimental background. J Prosthet Dent. 1983;50(3):399-10.
  5. PI B. Vital microscopy of bone marrow in rabbit. Scand J Clin Lab Invest. 1959;11:1-82.
  6. Wróbel E, Witkowska-Zimny M, Przybylski J. Biological mechanisms of implant osseointegration. Ortopedia, Traumatologia, Rehabilitacja. 2010;12(5):401-9.
  7. Bazal-Bonelli S, Sánchez-Labrador L, Cortés-Bretón Brinkmann J, Cobo-Vázquez C, Martínez-Rodríguez N, Beca-Campoy T, et al. Influence of serum vitamin d levels on survival rate and marginal bone loss in dental implants: a systematic review. Int J Environ Res Public Health. 2022;19(16):10120.
  8. Lin G, Ye S, Liu F, He F. A retrospective study of 30,959 implants: risk factors associated with early and late implant loss. J Clin Periodontol. 2018;45(6):733-43.
  9. Haderslev KV, Jeppesen PB, Sorensen HA, Mortensen PB, Staun M. Vitamin D status and measurements of markers of bone metabolism in Vitamin D effects on dental implant stability patients with small intestinal resection. Gut. 2003;52(5):653-8.
  10. Moreira ML, Neto LV, Madeira M, Lopes RF, Farias ML. Vitamin D deficiency and its influence on bone metabolism and density in a Brazilian population of healthy men. J Clin Densitom. 2018;21(1):91-7.
  11. Trybek G, Wlodarczyk MA, Kwiatek J, Preuss O, Brodkiewicz A, Sinicyn A, Grzywacz A. The effect of vitamin D3 on the osteointegration of dental implants. Balt J Health Phys Act. 2018;10(4):2.
  12. Fretwurst T, Grunert S, Woelber JP, Nelson K, Semper-Hogg W. Vitamin D deficiency in early implant failure: two case reports. Int J Implant Dent. 2016;2(1):24.
  13. Jasim HH, Aloosi SN. A novel approach for under preparation protocol in dental implant with low bone quality depending on hounsfield unit presurgically. Int J Health Sci. 2022;6(5):9808-22.
  14. Javed F, Malmstrom H, Kellesarian SV, Al-Kheraif AA, Vohra F, Romanos GE. Efficacy of vitamin D3 supplementation on osseointegration of implants. Implant Dent. 2016;25(2):281-87.
  15. Miri R, Shirzadeh A, Kermani H, Khajavi A. Relationship and changes of primary and secondary stability in dental implants: A review. Int J Contemp Dent Med Rev. 2017;2017.
  16. Makary C, Rebaudi A, Sammartino G, Naaman N. Implant primary stability determined by resonance frequency analysis: correlation with insertion torque, histologic bone volume, and torsional stability at 6 weeks. Implant Dent. 2012;21(6):474-80.
  17. Kwiatek J, Jaroń A, Trybek G. Impact of the 25-hydroxycholecalciferol concentration and vitamin d deficiency treatment on changes in the bone level at the implant site during the process of osseointegration: A prospective, randomized, controlled clinical trial. J Clin Med. 2021;10(3):526.
  18. Marheineke N, Scherer U, Rücker M, von See C, Rahlf B, Gellrich NC, Stoetzer M. Evaluation of accuracy in implant site preparation performed in single-or multi-step drilling procedures. Clin. Oral Investig. 2018;22(5):2057-67.
  19. Amr AE. Vitamin D3 in alveolar bone augmentation performed simultaneously with dental implant placement. A controlled clinical and radiographic study. Egypt Dent. 2019;65:3375-92 (Oral Medicine, X-Ray, Oral Biology & Oral Pathology).
  20. Mangano FG, Oskouei SG, Paz A, Mangano N, Mangano C. Low serum vitamin D and early dental implant failure: Is there a connection? A retrospective clinical study on 1740 implants placed in 885 patients. J Dent Res Dent Clin Dent Prospects. 2018;12(3):174.
  21. Lee HN, Kim MS, Lee JY, Zihan X, Ryu JJ, Shim JS. Reliability of implant stability measuring devices depending on various clinical conditions: an in vitro study. J Adv Prosthodont. 2023;15(3):126.
  22. Lin G, Ye S, Liu F, He F. A retrospective study of 30,959 implants: risk factors associated with early and late implant loss. J Clin Periodontol. 2018;45(6):733-43.
  23. Sargolzaie N, Samizade S, Arab H, Ghanbari H, Khodadadifard L, Khajavi A. The evaluation of implant stability measured by resonance frequency analysis in different bone types. J. Korean Assoc. Oral Maxillofac. Surg. 2019;45(1):29-33.
  24. Mangano F, Mortellaro C, Mangano N, Mangano C. Is low serum vitamin D associated with early dental implant failure? A retrospective evaluation on 1625 implants placed in 822 patients. Mediators Inflamm. 2016;2016.
  25. do Vale Souza JP, de Moraes Melo Neto CL, Piacenza LT, Freitas da Silva EV, de Melo Moreno AL, Penitente PA, et al. Relation between insertion torque and implant stability quotient: a clinical study. Eur J Dent. 2021;15(04):618-23.
  26. Mandal P, Karmakar A, Sen UK, Pahari S, Taraphdar S, Mukhopadhyay N. Bridge to integration and implant stability: A review. J Orofac Rehabil. 2023;3(2):9-16.
  27. Alvim‐Pereira F, Montes CC, Thomé G, Olandoski M, Trevilatto PC. Analysis of association of clinical aspects and vitamin D receptor gene polymorphism with dental implant loss. Clin Oral Implants Res. 2008;19(8):786-95.
  28. Lee J, Pyo SW, Cho HJ, An JS, Lee JH, Koo KT, et al. Comparison of implant stability measurements between a resonance frequency analysis device and a modified damping capacity analysis device: An in vitro study. J periodontal Implant Sci. 2020;50(1):56-66.
Statistics
  • Article view698
  • Downloads3
  • Published at1 August 2024

  • RIS
  • BibTeX
  • EndNote
  • Mendeley
  • APA (7th edition)
  • MLA (9th edition)
  • Chicago
  • Harvard
  • IEEE
  • Vancouver