Anti-Plaque and Anti-Inflammatory Effects of Prepared Punica Granatum Mouthwash on Patients with Moderate Gingivitis

Volume 4 , Issue 1 , December 2017 , Pages 1-14

Authors

Chinar A. Mohammed 1 ; Amal H. Aziz 1 ; Shima G. Thanoon 2

1 Department of Periodontics, College of Dentistry, Hawler Medical University, Erbil, Iraq.

2 Department of Oral Diagnosis, College of Dentistry, Hawler Medical University, Erbil, Iraq.

DOI logo 10.17656/sdj.10065

Keywords

Abstract

Objective: Punica granatum is a herbal product used in the field of dentistry which has many potential effects including
bactericidal, antifungal, antiviral, and immune modulation. This study aimed to evaluate the effect of prepared Punica
granatum as an antiplaque and anti-inflammatory agent in the treatment of gingival inflammation.
Methods: Sixty patients were enrolled in this study. Fourty five patients with moderate gingivitis were divided randomly
into 3 groups; chlorhexidine group included 15 patients received once-daily dose of chlorhexidine mouthwash for 1 day,
Punica I group included 15 patients received once-daily dose of Punica mouthwash for 1 day, and Punica II group included
15 patients received once-daily dose of Punica mouthwash for 2 consecutive days. Plaque index, gingival index, and
bleeding on probing were assessed before rinsing and after 3 and 7 days of rinsing, also saliva were collected before rinsing
and after 1 hour, 2 hrs, 1 and three days of rinsing to estimate the level of interleukine-1β. The rest 15 subjects were with
clinically healthy gingiva.
Results: Punica II group resulted in significant reduction of plaque index, gingival index, and bleeding on probing after 3
and 7 days of rinsing (p≤0.05) but with non-significant differences with chlorhexidine group (p>0.05). It had significant
effect in reduction of interleukine-1β which begin after one day of rinsing and continued into three days (p≤0.05).
Conclusions: Punica like chlorhexidine has a positive effect on reduction of plaque accumulation and improvement of
gingival inflammation so can be used as an anti-plaque and anti-inflammatory agent in the treatment of gingival
inflammation. 

Statistics
  • Article view679
  • Downloads5
  • Published at1 December 2017

  • RIS
  • BibTeX
  • EndNote
  • Mendeley
  • APA (7th edition)
  • MLA (9th edition)
  • Chicago
  • Harvard
  • IEEE
  • Vancouver